�cole sup�rieure de chimie organique et min�rale

�cole sup�rieur de chimie organique et min�rale

Conférences

Invités

"Potential uses of pollen and spore shells :
drug delivery, imaging, food, drinks, cosmetics & solid supported reagents"

Grahame Mackenzie PhD, CChem, FRSC
Reader in Bioorganic Chemistry
Department of Chemistry
University of Hull

Abstract


The talk covered the extraction of sporopollenin exines which are the shells of pollens and spores. An outline was given relating to some of the physical and chemical properties of sporopollenin exines, in particular their physical and chemical resilience and their uniformity. Mention was made of their ability to act as microcapsules and their potential to be applied to drug deliver. Also discussed are results indicating the antioxidant properties of pollen extracts. Evidence was given to show how sporopollenin exines have been used as imaging agents in Magnetic Resonance Imaging. Finally some basic chemistry and modifications of sporopollenin was discussed indicating potential applications in such as drug delivery, solid supported synthesis and ion exchange chromatography.(More information can be found on (www.sporomex.co.uk)

 

Recent references :


1. Sporopollenin exines : A novel natural taste masking material
Sylvain Barrier, Alan S. Rigby, Alberto Diego-Taboada, Matthew J. Thomasson,
Grahame Mackenzie, Stephen L. Atkin.
LWT - Food Science and Technology 2010, 43, 73–76

2. Access to a primary aminosporopollenin solid support from plant spores. Sylvain Barrier, Andreas Löbbert, Alia J. Boasman, Andrew N. Boa, Mark Lorch, Stephen L. Atkin and Grahame Mackenzie. Green Chem., 2010, 12, 234 - 240, DOI : 10.1039/b913215e

3. MRI contrast agent delivery using spore capsules : controlled release in blood plasma
Mark Lorch,a Matthew J. Thomasson,a Alberto Diego-Taboada,a Sylvain Barrier,a
Stephen L. Atkin,b Grahame Mackenziea and Stephen J. Archibald.
Chem. Commun., 2009, 6442–6444.

More informations : http://www.hull.ac.uk/chemistry/academic_staff.php?id=gm

 

 

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